The record for August 22 in baseball history — 10 milestones, 17 debuts, 8 final games, 62 births, 21 deaths and 1,399 games played.
Texas Rangers pitcher Nolan Ryan strikes out Oakland Athletics leadoff man Rickey Henderson to become the first pitcher in Major League history to record 5,000 career strikeouts.
Honus Wagner hit for the cycle for the Pittsburgh Pirates against the New York Giants on August 22, 1912.
Frank Robinson hit three home runs for the Cincinnati Redlegs against the St. Louis Cardinals on August 22, 1959.
San Francisco Giants pitcher Juan Marichal strikes Los Angeles Dodgers catcher John Roseboro on the head with his bat during a heated rivalry game, sparking a bench-clearing brawl and a lengthy suspension.
Texas Rangers pitcher Nolan Ryan strikes out Oakland Athletics leadoff man Rickey Henderson to become the first pitcher in Major League history to record 5,000 career strikeouts.
Sammy Sosa hit three home runs for the Chicago Cubs against the Milwaukee Brewers on August 22, 2001.
Nick Markakis hit three home runs for the Baltimore Orioles against the Minnesota Twins on August 22, 2006.
Adrian Beltré hit three home runs for the Texas Rangers against the Baltimore Orioles on August 22, 2012.
Adrián González hit three home runs for the Los Angeles Dodgers against the Cincinnati Reds on August 22, 2016.
José Abreu hit three home runs for the Chicago White Sox against the Chicago Cubs on August 22, 2020.
Trent Grisham hit three home runs for the San Diego Padres against the Houston Astros on August 22, 2020.
John O'Connell made a major-league debut on August 22, 1891.
Kitty Bransfield made a major-league debut on August 22, 1898.
Lou North made a major-league debut on August 22, 1913.
Rudy York made a major-league debut on August 22, 1934.
Preacher Roe made a major-league debut on August 22, 1938.
Jack Phillips made a major-league debut on August 22, 1947.
Dale Berra made a major-league debut on August 22, 1977.
Ken Oberkfell made a major-league debut on August 22, 1977.
Junior Noboa made a major-league debut on August 22, 1984.
Mark McGwire made a major-league debut on August 22, 1986.
Marquis Grissom made a major-league debut on August 22, 1989.
Reggie Sanders made a major-league debut on August 22, 1991.
Torii Hunter made a major-league debut on August 22, 1997.
Eric Byrnes made a major-league debut on August 22, 2000.
Dustin Pedroia made a major-league debut on August 22, 2006.
Jordan Walden made a major-league debut on August 22, 2010.
Yacksel Ríos made a major-league debut on August 22, 2017.
Art Whitney played a final major-league game on August 22, 1891.
Jack Kramer played a final major-league game on August 22, 1951.
Wilbur Wood played a final major-league game on August 22, 1978.
Jody Reed played a final major-league game on August 22, 1997.
Sterling Hitchcock played a final major-league game on August 22, 2004.
J. C. Romero played a final major-league game on August 22, 2012.
Rafael Betancourt played a final major-league game on August 22, 2015.
Francisco Cervelli played a final major-league game on August 22, 2020.
Cleveland Guardians 3, Texas Rangers 4.
St. Louis Cardinals 6, Tampa Bay Rays 10.
Athletics 2, Seattle Mariners 3.
Boston Red Sox 1, New York Yankees 0.
Kansas City Royals 5, Detroit Tigers 7.
Minnesota Twins 9, Chicago White Sox 7.
Houston Astros 10, Baltimore Orioles 7.
Chicago Cubs 3, Los Angeles Angels of Anaheim 2.
Los Angeles Dodgers 1, San Diego Padres 2.
Colorado Rockies 0, Pittsburgh Pirates 9.
Washington Nationals 5, Philadelphia Phillies 4.
San Francisco Giants 4, Milwaukee Brewers 5.
These are the 12 most recent of 1,399 games played on this date. The sections above lead with what made the day matter.
62 players were born on August 22; these are the 24 best known.