Nick Markakis's Three-Home-Run Game, 2006

Nick Markakis hit three home runs in one game for the Baltimore Orioles against the Minnesota Twins on August 22, 2006. The Baltimore Orioles won 6–3.

The game was played at Oriole Park at Camden Yards in Baltimore. The announced attendance was 19,756. The game took 2h 23m. It was a night game under cloudy skies, at 89 degrees.

It was the only time Nick Markakis managed it. Carlos Silva started for the Minnesota Twins. Randy Marsh umpired behind the plate. It is the eighth of eleven three-home-run games the archive records that season.