Matt Cain's Perfect Game

Matt Cain threw a perfect game for the San Francisco Giants against the Houston Astros on June 13, 2012. No batter reached base: twenty-seven faced, twenty-seven retired. The final score was 10–0.

The game was played at AT&T Park in San Francisco. Matt Cain struck out 14. The announced attendance was 42,298. The game took 2h 36m. It was a night game under sunny skies, at 59 degrees.

It is the nineteenth of 21 perfect games the archive records between 1904 and 2023. It was the only one of Matt Cain's career. It was one of seven no-hitters thrown across the major leagues in 2012. J. A. Happ took the loss for the Houston Astros. The Houston Astros used three pitchers of their own. Ted Barrett umpired behind the plate.