Edwin Encarnación's Three-Home-Run Game, 2010

Edwin Encarnación hit three home runs in one game for the Toronto Blue Jays against the Arizona Diamondbacks on May 21, 2010. The Toronto Blue Jays lost 8–6.

The game was played at Chase Field in Phoenix. The announced attendance was 19,531. The game took 2h 50m. It was a night game under sunny skies, at 95 degrees.

Edwin Encarnación did it three times in all. Dan Haren started for the Arizona Diamondbacks. Mike Muchlinski umpired behind the plate. It is the third of thirteen three-home-run games the archive records that season.